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Anticoagulated guinea pig blood suitable for use in complement titration, adsorption procedures, testing for agglutinins/HA assays, and the preparation of stroma as particulate reagents.
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A glycine-conjugated form of chenodeoxycholic acid; reduces formation of cholic acid in primary human hepatocytes at 100 µM; reduces the number LC3 puncta and is cytotoxic to L-02 hepatocytes at 50, 75, and 100 µM; induces apoptosis in isolated rat hepatocytes at 50 µM; fecal levels are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An orally bioavailable selective inhibitor of PDGFRa PDGFRB and FLT3 (IC50s 11 3 2 and 4 nM respectively) also inhibits mutant forms of these kinases including the D842V-containing form of PDGFR and D835Y and internal tandem duplication mutations of FLT3 at nanomolar concentrations
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An antagonist of mGluR1 and mGluR2 selective for mGluR1 and mGluR2 over mGluR6 at 1 mM inhibits L-glutamate-induced increases in InsPs in CHO cells expressing mGluR1 and prevents forskolin-induced decreases in cAMP in CHO cells expressing mGluR2 at 1 mM intraplantar administration reduces glutamate-induced paw licking in a mouse model of nociceptive pain at 1-10 nmol/paw
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An inhibitor of the gastric H /K ATPase and an enantiomer of esomeprazole inhibits histamine-induced acid secretions in isolated rabbit gastric glands (IC50 781 UM) to a lesser extent than esomeprazole inhibits histamine-induced stomach acid secretion in rats at 30 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More